From Homestar Runner Wiki
The programming of the long-running children's channel, Nickelodeon, has inspired some short gags in Homestar Runner. Matt Chapman currently works for the channel, being a director of the Nick Jr. show Yo Gabba Gabba!; he and Mike had previously animated a cartoon for that show.
- Sketchbook (museum) — The caption for the Trivia Time sketches reads, "Is that Stimpy?"
- Email 12:00 (Easter egg) — One of the tapes in the VCR reads "YCDTOTV Season 2", for the show You Can't Do That on Television.
- Puppet Time — Homestar Runner drops off a video of Mr. Wizard.
- Email for kids — In Strong Bad's children show, he asks viewers to help him find The Cheat. This is similar to early episodes of Blue's Clues that began with the host, Steve, asking the viewers to help find Blue.
- The Li'l Brudder Show — Li'l Brudder scrapes across the show's logo as SpongeBob SquarePants does in the opening of his show.
- Teen Girl Squad Issue 10 — What's Her Face asks The Ugly One if her party will be "Nick-at-Nite themed again".
- Jibblies 2 — The Cheat dresses as Penfold from DangerMouse. Homestar dresses as Artie from The Adventures of Pete and Pete. Bubs dresses as Ross from YCDTOTV. Marzipan gets slimed for saying "I don't know" (like the cast of YCDTOTV occasionally did).
- Decemberween Short Shorts (DVD commentary) — Matt Chapman says the shot of Coach Z's butt reminds him of Ren and Stimpy. Mike Chapman says there might have been butt dancing in "Happy Happy Joy Joy", a song from that show.
- Toikey TV — The title is a parody of Turkey TV.
- Sketchbook — The entry "Puddin' Patch Friends" includes a drawing of Dora the Explorer.
- Most in the Graveyard — Coach Z dresses up as DJ Lance Rock from Yo Gabba Gabba!.
- Email original (DVD commentary) — Bubs says that Original Bubs looks like Rocko's Modern Life.