From Homestar Runner Wiki
Melonade is a preferred drink of Homestar Runner. It first appeared in "A Jumping Jack Contest", where The Cheat offered Homestar 147 glasses of it, and got refills from Strong Mad's melonade keg. Homestar Runner usually eats about 147 Fluffy Puff Marshmallows before drinking a tall glass of melonade. Melonade derives its name from the similarly formulated drink, lemonade, which is made from lemons rather than melons. In addition, the words "melon" and "lemon" are anagrams.
During melonade shortages, it can sell for as much as $2 per gallon.
According to the retro-themed Hremail 7, Homestar once had an endorsement deal with The Ethical Advancement of Melonade that made him "contractually unable to drink, talk about, or bathe in any other liquid". According to the hremail, said contract expired in March of 2003. During this email, several variants of Melonade were mentioned.
 Melonade Variants
- Debut: A Jumping Jack Contest
- The Luau (mentioned)
- Fluffy Puff Commercial (mentioned)
- Main Page 11
- Email helium
- Email cheat talk (mentioned in Easter egg)
- Tis True, Pom Pom, Tis True
- Email anything
- Halloween Potion-ma-jig (mentioned)
- No Hands On Deck!
- Everything Else, Volume 3 (on the cover, and on the Toons menu)
- Email hiding
- Homestar Ruiner
- Best Caper Ever (mentioned)
- Where U Goin' 2?
- Hremail 7
- Marzipan's Answering Machine Version 17.2 (mentioned)